UNERA - Unidad de Enfermedades Reumáticas y Autoinmunes

Protocolos de Manejo de Artritis Reumatoide

Dr. Luis Zurita - Dr. Claudio Galarza

BIBLIOGRAFÍA

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63 Makinen H, Kautiainen H, Hannonen P et al. Sustained remission and reduced radiographic progression with combination disease modifying antirheumatic drugs in early rheumatoid arthritis. Journal of Rheumatology. 2007;34(2):316–321.

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68 Landewe RB, Boers M, Verhoeven AC et al. COBRA combination therapy in patients with early rheumatoid arthritis: long-term structural benefits of a brief intervention. Arthritis & Rheumatism. 2002;46(2):347–356.

69 Capell HA, Madhok R, Porter DR et al. Combination therapy with sulfasalazine and methotrexate is more effective than either drug alone in patients with rheumatoid arthritis with a suboptimal response to sulfasalazine: results from the double-blind placebo-controlled MASCOT study. Annals of the Rheumatic Diseases. 2007;66(2):235–241.

70 Allaart CF, Goekoop-Ruiterman YP, De Vries-Bouwstra JK et al. Aiming at low disease activity in rheumatoid arthritis with initial combination therapy or initial monotherapy strategies: the BeSt study. Clinical & Experimental Rheumatology. 2006;24(6 suppl 43):1–77.

71 Goekoop-Ruiterman YP, de Vries BJK, Allaart CF et al. Comparison of treatment strategies in early rheumatoid arthritis: a randomized trial. Ann Intern Med. 2007;146(6):406–415.

72 Goekoop-Ruiterman YP, De Vries-Bouwstra JK, Allaart CF et al. Clinical and radiographic outcomes of four different treatment strategies in patients with early rheumatoid arthritis (the best study): A randomized, controlled trial. Arthritis & Rheumatism. 2005;52(11):3381–3390.

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74 Ferraccioli GF, Gremese E, Tomietto P et al. Analysis of improvements, full responses, remission and toxicity in rheumatoid patients treated with step-up combination therapy (methotrexate, cyclosporin A, sulphasalazine) or monotherapy for three years. Rheumatology. 2002;41(8):892–898.

75 Choy EH, Smith CM, Farewell V et al. Factorial randomised controlled trial of glucocorticoids and combination disease modifying drugs in early rheumatoid arthritis. Annals of the Rheumatic Diseases.2008;67(5):656–663.

76 Braun J, Kastner P, Flaxenberg P et al. Comparison of the clinical efficacy and safety of subcutaneous versus oral administration of methotrexate in patients with active rheumatoid arthritis: results of a six-month, multicenter, randomized, double-blind, controlled, phase IV trial. Arthritis & Rheumatism. 2008;58(1): 73–81.

77 Hider SL, Silman A, Bunn D et al. Comparing the long-term clinical outcome of treatment with methotrexate or sulfasalazine prescribed as the first disease-modifying antirheumatic drug in patients with inflammatory polyarthritis. Annals of the Rheumatic Diseases. 2006;65(11):1449–1455.

78 Aetna. Remicade: Clinical Policy Document. 28 October 2005. 0341 Revised.

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80 Smolen JS, Han C, Bala M et al. ATTRACT Study Group. Evidence of radiographic benefit of treatment with infliximab plus methotrexate in rheumatoid arthritis patients who had no clinical improvement. Arthritis Rheum 2005;52:1020–30.

81 Keystone EC, Kavanaugh AF, Sharp JT et al. Radiographic, clinical, and functional outcomes of treatment with adalimumab (a human anti-tumor necrosis factor monoclonal antibody) in patients with active rheumatoid arthritis receiving concomitant methotrexate therapy. Arthritis Rheum 2004;50:1400–11.

82 Klareskog L, van der Heijde D, de Jager JP et al. TEMPO (Trial of etanercept and methotrexate with radiographic patient outcomes) study investigators. Therapeutic effect of the combination of etanercept and methotrexate compared with each treatment alone in patients with rheumatoid arthritis: double-blind randomized controlled trial. Lancet 2004;363:675–81.

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84 Tak et al., EULAR 2009, Abstract OP-0022

85 Rigby et al., EULAR 2009, Abstract SAT0121

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87 Emery P, Rigby W, Combe B, et al. Efficacy and Safety of Rituximab (RTX) as First-Line Biologic Therapy in Patients (pts) with Active Rheumatoid Arthritis (RA): Results of a Phase III Randomized Controlled Study (SERENE). Available at

88 Cohen SB, Emery P, Greenwald MW, et al; for the REFLEX Trial Group. Rituximab for rheumatoid arthritis refractory to anti–tumor necrosis factor therapy: results of a multicenter, randomized, double-blind, placebo-controlled, phase III trial evaluating primary efficacy and safety at twenty-four weeks. Arthritis Rheum. 2006;54(9):2793-2806.

89 Keystone E, Emery P, Peterfy CG, et al. Prevention of joint structural damage at 1 year with rituximab in rheumatoid arthritis patients with an inadequate response to one or more TNF inhibitors (REFLEX study) [abstract OP0016]. Ann Rheum Dis. 2006;65(suppl II):58.

90 Luggen M, Emery P, Li T, McCann T, Teng J, Schiff M. Abatacept provided clinically meaningful improvements in multiple aspects of health related quality of life (HRQoL) and physical function through 2 years of treatment in patients with active rheumatoid arthritis (RA): results from the AIM and ATTAIN trials. Poster presentation Monday, November 13, 2006, Poster no 980 at: American College of Rheumatology annual scientific meeting. Washington DC, November 10-15, 2006.

91 Dougados M, Russell A, Li T, Sherrer Y, Teng J, McCann T, Westhovens R. Abatacept provides sustained improvements in pain, fatigue and sleep quality through 2 years in the treatment of rheumatoid arthritis patients in the AIM and ATTAIN trials. Poster presentation Sunday, November 12, 2006, poster no 502 at: American College of Rheumatology annual scientific meeting. Washington DC, November 10-15, 2006.

92 Genovese M, Schiff M,Luggen M, Becker J-C, Aranda R, McCann T,Schmidely N, Le Bars M, Dougados M, Sustained Efficacy and Safety Through 2 Years in Patients with Rheumatoid Arthritis in the Long-term Extension of the ATTAIN Trial. Poster presentation Sunday, November 12, 2006, Poster no 498 at: American College of Rheumatology annual scientific meeting. Washington DC, November 10-15, 2006.

93 Weinblatt, B Combe, C Birbara, A Covucci, T Li, J-C Becker, R Aranda, E Keystone. Safety and Patient-reported Outcomes Through 2 Years of Treatment with Abatacept in Rheumatoid Arthritis Patients Receiving Background Disease-modifying Antirheumatic Drugs (DMARDs): The ASSURE Trial. Poster presentation Sunday, November 12, 2006, poster no 509 at: American College of Rheumatology annual scientific meeting. Washington DC, November 10-15, 2006.

94 Genovese MC, Becker JC, Schiff M, Luggen M, Sherrer Y, Kremer J, et al. Abatacept for rheumatoid arthritis refractory to tumor necrosis factor alpha inhibition. N Engl J Med. 2005;353:1114-23.

95 Maini RN, Taylor PC, Szechinski J, Pavelka K, Broll J, Balint G,et al, for the CHARISMA Study Group. Double-blind randomized 2978 GENOVESE ET AL controlled clinical trial of the interleukin-6 receptor antagonist, tocilizumab, in European patients with rheumatoid arthritis who had an incomplete response to methotrexate. Arthritis Rheum 2006;54:2817–29.

96 Nishimoto N, Hashimoto J, Miyasaka N, Yamamoto K, Kawai S, Takeuchi T, et al. Study of active controlled monotherapy used for rheumatoid arthritis, an IL-6 inhibitor SAMURAI): evidence of clinical and radiographic benefit from an x ray reader-blinded randomised controlled trial of tocilizumab. Ann Rheum Dis 2007;66:1162–7.

97 Nishimoto N, Yoshizaki K, Miyasaka N, Yamamoto K, Kawai S, Takeuchi T, et al. Treatment of rheumatoid arthritis with humanized anti–interleukin-6 receptor antibody: a multicenter, doubleblind, placebo-controlled trial. Arthritis Rheum 2004;50:1761–9.

98 Smolen JS, Beaulieu A, Rubbert-Roth A, Ramos-Remus C, Rovensky J, Alecock E, et al. Effect of interleukin-6 receptor inhibition with tocilizumab in patients with rheumatoid arthritis (OPTION study): a double-blind, placebo-controlled, randomized trial. Lancet 2008;371:989–97.

99 Mark C. Genovese, James D. McKay, Evgeny L. Nasonov,et al. Interleukin-6 Receptor Inhibition With Tocilizumab Reduces Disease Activity in Rheumatoid Arthritis With Inadequate Response to Disease-Modifying Antirheumatic Drugs. Arthritis Rheum 2008;58:2968-2980

100 Emery P, Keystone E, Tony HP, Cantagrel A, Van Vollenhoven R, Sánchez A. IL-6 receptor inhibition with tocilizumab improves treatment outcomes in patients with rheumatoid arthritis refractory to anti-tumour necrosis factor biologicals: Results from a 24-week multicentre randomised placebo-controlled trial. Ann Rheum Dis. 2008;67:1516-1523.

101 Jones G, Gu JR, Lowenstein M. Tocilizumab monotherapy is superior to methotrexate monotherapy in reducing disease activity in patients with rheumatoid arthritis: The AMBITION study. Ann Rheum Dis. 2008;67:89.

102 Kremer JM, Fleischmann RM, Halland AM, Brzezicki J, Woodworth T, Fisheleva E. Tocilizumab inhibits structural joint damage in rheumatoid arthritis patients with an inadequate response to methotrexate: The LITHE study. Arthritis Rheum. 2008;58:L11.

103 Keane J, Gershon S, Wise RP, Mirabil-Levens E, Kasznica J, Schwiterman WD, et al. Tuberculosis associated with infliximab, a tumor necrosis factor alpha-neutralizing agent. N Engl J Med. 2001;345:1098-104.

104 Gomez-Reino JJ, Carmona L, Rodriguez-Valverde V, Martin-Mola E, Moreno C, et al, on behalf of the BIOBADASER Group. An active surveillance of rheumatoid arthritis patients treated with tumor necrosis factor inhibitors indicates significant tuberculosis risk increase. Arthritis Rheum. 2003;48:2122-7.

105 F. Tubach, D. Salmon, P. Ravaud, et al. Risk of Tuberculosis Is Higher With Anti–Tumor Necrosis Factor Monoclonal Antibody Therapy Than With Soluble Tumor Necrosis Factor Receptor Therapy. Arth and Rheum 2009:60;1884-1894

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110 Mohan N, Edwards ET, Cupps TR, Oliverio PJ, Sanberg G, Crayton H, et al. Demyelination occurring during anti-tumor necrosis factor a therapy for infflammatory arthritides. Arthritis Rheum. 2001;44:2862-9.

111 Wolfe F, Michaud K. Lymphoma in rheumatoid arthritis: the effect of methotrexate and anti-tumor necrosis factor therapy in 18,572 patients. Arthritis Rheum. 2004;50:1740-51.

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117 Furst DE, Schiff MH, Fleischmann RM et al. Adalimumab, a fully human anti tumor necrosis factor-alpha monoclonal antibody, and concomitant standard antirheumatic therapy for the treatment of rheumatoid arthritis: results of STAR (Safety Trial of Adalimumab in Rheumatoid Arthritis). J Rheumatol 2003;30:2563–71.

118 Cheifetz A, Smedley M, Martin S et al. The incidence and management of infusion reactions to Infliximab: a large center experience. Am J Gastroenterol 2003;98:1315–24.

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122 van Vollenhoven R, Harju A, Brannemark S, Klareskog L. Treatment with infliximab (Remicade) when etanercept (Enbrel) has failed or vice versa: data from the STURE registry showing that switching tumour necrosis factor alpha blockers can make sense. Ann Rheum Dis 2003;62:1195–8.

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INTRODUCCIÓN  |  CONTENIDO  |  AUTORES  |  BIBLIOGRAFÍA

 

Información de los Autores

 

Dr. Luís Zurita Gavilanes

Consultorio Sur: Centro Médico Alcívar No. 4. Coronel 2207 y Cañar. Of 10 y 11.
Teléfonos: (5934) 2337330-3    

Consultorio Norte: Centro de Diagnóstico Médico Gamma CLÍNICA KENNEDY Av. 10a y Callejón 11 - A, N.O. Of. # 105.
Teléfonos: (5934) 2397438 - 2397439 
E-mail: info@artritisylupus.com

Guayaquil, Ecuador.

 

Dr. Claudio Galarza Maldonado

Consultorio: Hospital Monte Sinaí, Miguel Cordero 611 y Av. Solano.

Teléfono: (5937) 2885595

E-mail: claudiogalarza@hotmail.com

Cuenca, Ecuador.

›Diseñado por www.medicosecuador.com